Microsoft Office 365 is a subscription option for Microsoft Office software. It features the same productivity applications -- Word, Excel, PowerPoint, Access, Outlook, Publisher, and Infopath -- but has the advantage of cloud-based storage and automatic updates. This means you can access your files from virtually any location with an Internet connection and use multiple devices including PCs, Macs, and tablets.

Microsoft Office 2016 is a suite of applications available for both Windows and Mac that users install on their computer. Office 2016 also includes applications just like Word, Excel, PowerPoint, Access, Outlook, Publisher, and Infopath for use within a single PC or Mac. The suite supports PCs running Windows 7 or higher and Macs running Mac OS X 10.10 for Office 2016 for Mac.